DIABETES COMPLICATIONS
Severe long-term complications of diabetes include: cardiovascular diseases, chronic kidney failure (also known as diabetic nephropathy), neuropathy, and microvascular complications. Among these, microvascular complications?can lead to impaired wound healing. JOINN's diabetes complication models include:
|
?Indication |
?Model |
?Species |
|
?Diabetic nephropathy |
?STZ + nephrectomy?+ high salt load |
?rat, mice |
|
?Delayed diabetic wound healing |
?STZ-induced T1DM +?skin excision |
?rat |
|
?T2DM + skin excision |
?db/db |
|
|
?ZDF rat |
||
|
?Diabetic neuralgia |
?STZ-induced T1DM |
?mice |
